AZDye 488 Tetrazine (CCT-1361)

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Description

A bright, green-fluorescent probe used for detection TCO-tagged biopolymers. AZDye 488 Tetrazine demonstrates exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctenes (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. In applications such as in vivo cancer imaging or pre‐targeted cell labeling studies where rapid reaction kinetics is a must AZDye 488 Tetrazine probe would of great value.

Specifications

Unit Size1 mg, 5 mg, 25 mg
Abs/Em Maxima493/517 nm
Extinction Coefficient
83,000
Flow Cytometry Laser Line
488 nm
Microscopy Laser Line
488 nm
Spectrally Similar DyesAlexa Fluor® 488, Atto™ 488, CF™ 488 Dye, DyLight™488
Molecular weight703.66
CASN/A
SolubilityWater, MeOH, DMSO, DMF
Purity>95% (HPLC)
AppearanceRed solid
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Abs/Em Spectra

Documents

Selected References

  1. Marquard, A.N., et al. (2020). Expanding the Scope of Antibody Rebridging with New Pyridazinedione-TCO Constructs. Bioconjug Chem.31(6), 1616-23. [PubMed]

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