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Mono-sulfone is a thiol-specific labeling reagent that undergo alkylation to generate a thio-ether bond between the protein and mono-sulfone activated reagent. Once mono-sulfone reagent is conjugated to a protein or peptide, exchange reactions leading to deconjugation can be easily avoided by treating the conjugate with a mild reducing agent in a way analogous to the process used for conjugation reactions involving reductive amination.
| Unit Size | 1000 mg, 5 g |
|---|---|
| Molecular weight | 492.44 |
| Chemical composition | C21H19NO7S |
| CAS | N/A |
| Solubility | DMSO, DMF, DCM, THF, Chloroform |
| Purity | >95% (HPLC) |
| Appearance | Grey solid |
| Storage Conditions | -20°C. Desiccate |
| Shipping Conditions | Ambient temperature |
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