TCO-PEG4-NHS Ester (CCT-A137)

Description

TCO-PEG4-NHS Ester is a pegylated lebeling reagent with enhanced solubility in aqueous buffers used for TCO labeling of antibodies, proteins and other primary amine-containing macromolecules. A long, hydrophilic PEG4 spacer arm provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary tetrazine-containing molecules.

Specifications

Documents

Selected References

1. Ingham, E. S., et al. (2020). Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation. Nat Commun, 11, 2102. [Nature Communications]
2. Sun, N., et al. (2020). Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring. Nat Commun., 11, 4489. [PubMed]
3. Allo, B., et al. (2018). Clickable and High-Sensitivity Metal-Containing Tags for Mass Cytometry. Bioconjugate Chem. , 29(6), 2028-38. [PubMed]